Dongzi YANG (China)
Professional Experience:
2017-now Professor, , Division of Reproductive Medicine, Dept. OB/GYN,Memorial Hospital, Sun Yat-Sen University (SYSU),Guangzhou, China
1998-2017: Professor, Chairperson, Dept. OB/GYN, and Director of Division of Reproductive Medicine, Memorial Hospital, Sun Yat-Sen University (SYSU),Guangzhou, China
1993-1998 Associate Professor , Dept. of OB/GYN, Memorial Hospital, SUMS, Guangzhou, China
1988-1993 Lecturer and Attending ,Dept. of OB/GYN, Memorial Hospital, SUMS, Guangzhou, China
1982-1988 Resident ,Dept. OB/GYN, Memorial Hospital, SUMS, Guangzhou, China
Education & Training
1982, M.D., Department of Medicine, Sun Yat-Sen University of Medical Sciences.
1990, Ph.D., Department of Medicine, Sun Yat-Sen University of Medical Sciences.
1996, Advanced training of ART in Queen Mary Hospital of Hong kong
2000 ~2001, Hubert. H. Humphrey Fellowship, Training in Reproductive medicine at Emory University and University of California, San Diego, U.S.A
SOCIETIES/COMMITTEES/PROFESSIONAL ACTIVITIES:
- Vice-President of Chinese Reproductive Medicine Association of CMDA
- Deputy- editor in chief of Chinese Journal of Obstetrics and Gynecology,
- Vice-President of Reproductive Medicine Association of CPAM (Chinese International Exchange and Promotion Association for Medical and Health Care)
- Standing Board member , Gynecology and Obstetrics Society of Chinese Medical Association
- President, Gynecologist and Obstetrician Society of Guangdong Provincial Medical Doctoral Association
- Assistant Chair , Gynecological Endocrinology group of of Gynecology and Obstetrics Society of Chinese Medical Association
- Reviewer for numerous journals, e.g.International Journal of Obstetrics & Gynecology and Reproductiv, Biomedical online.
Publications:
Books: Chief Editor of 5 books; Member of Editor board of 20 books
Papers: published over 200 original articles including 50 peer-reviewed papers:
Abstract
The Autoimmune Bases of Infertility and Repeated Implantation Failure After IVF/ICSI-ET
Recurrent implantation failure (RIF) after IVF-ET and recurrent pregnancy loss (RPL) remains a common problem, which occurs in 1%-5% of couples of reproductive age. The aetiologies of RIF and RPL include maternal imbalances immune system. However, the nature of immune alterations in RIF and RPL remains ill-defined with limited evidence for suitable immune biomarkers to identify patients that may be suitable for immunomodulating treatment. Aspecific auto-immunity defined as positivity of auto-antibodies in blood sample without clinical or biological criteria for defined diseases. The presence of anti-thyroperoxydase antibodies and/or throglobulin are related to infertility; anti-phospholipid (APL) and/or anti-nuclear (ANA) antibodies are more frequent in the population of infertility women. Current treatment modalities include immunomodulating and immunosuppressive therapies. But there are no large randomised controlled trials to deliver high-level evidence of clinical benefit. We examine the currently available evidence for immunological focussed laboratory testing to guide treatments for RIF.